Hymenopappus mexicanus grows mainly in the mountains of central and east Arizona, plus some scattered locations in New Mexico, and the two adjacent states of Mexico. Leaves may be unlobed, but are usually divided into two to seven pairs of relatively broad lobes, hairless or sparsely hairy. This distinguishes the plant from the otherwise similar, and more widespread
hymenopappus filifolius. Leaves are mostly basal; there may also be a few stem leaves. A single plant can produce up to 20 stems.
The inflorescence is an open cluster, with (usually) two to eight flowerheads, which have disc florets only, numbering from 20 to 40. The equal-length phyllaries are light green, and hairy, sometimes yellowish or reddish.