Pads of
opuntia gosseliniana may be purple or green depending on environmental conditions; when purple the species resembles
opuntia santa rita, which is found in the same area, but this has generally shorter spines (or no spines), larger pads and forms larger clusters. The cactus also has similarities to
opuntia macrocentra, and is sometimes classed as a variety of
opuntia chlorotica. Spine cover is variable; some areoles have none, others (towards the pad edges) have from 1 to 4 spines, white or brownish. Glochids are also more pronounced around the edges of the pads.